The automated thermal cycler Biometra TRobot II allows a high-throughput PCR workflow with 24/7 reliable, unattended operation with highest quality of results for routine PCR or incubation applications. It is ideal for molecular biology labs that face a large number of samples every day and need to rely on the analysis results of their valuable samples.

High Degree of Automation for More Efficiency

  • Space-saving modular concept
  • Direct access to the sample block from three sides
  • Trouble-free removal of plates thanks patent-pending plate lifting system
  • Gradient function for optimization of new protocols
  • Touch-sensitive safety frame at the lid for maximum user-safety
  • Robust design for 24/7 use in automated systems
  • Whisper quiet for high user convenience
  • Patent-pending automated Smart Tune Lid ensures uniform conditions in all sample positions

Product Highlights in Detail

Always best results

In addition to the typical main application, the polymerase chain reaction (PCR), the Biometra TRobot II is also suitable for all other molecular biological or chemical incubations in PCR plates. For example, the generation of libraries for Next Generation Sequencing (NGS) is an important step in a larger workflow where the automated thermal cycler can be used. This reduces the manual effort and the possibility of errors. The PCR cycler has outstanding heating and cooling rates and excellent temperature homogeneity across the sample block for highly reproducible PCR results. For the setup of new protocols or for the transfer of existing protocols from other thermal cyclers it is sometimes necessary to make slight optimizations to the protocols. For this purpose the Biometra TRobot II includes a gradient function. With this function it is possible, to test different temperatures in the critical annealing step of the PCR in one run.

Fit for integration

In automated systems, compact components with the smallest possible footprint are particularly important. The Biometra TRobot II meets this requirement through its modular design with a compact PCR module that is placed directly on the automation deck, while the controller can be stored underneath the platform. Another important point in automation is that all components should be very robust and reliable. If one component fails, the entire workflow comes to a halt. With this background, we have developed a special, patent-pending mechanism for opening and closing the lid of the Biometra TRobot II, which is intended for permanent use. At the same time, the block design was designed to enable the gripper to access the sample block from three sides. This opens up many possibilities for positioning the thermal cycler on the deck.

Ease of work

A conveniently prepared library allows a fast integration into automation systems. In addition, powerful computer software, the Biometra TSuite, is available for direct control of the automated thermal cycler, which is helpful for first PCR runs in preparation for the actual application. Maximum user safety is ensured with a unique, touch-sensitive safety frame which immediately stops the lid closing in case of contact with a resistance. The smooth block surface without gaps is essential for easy and effective cleaning and decontamination. For stress-free work it is also important to keep the noise level low. The ventilation system has been designed to remain very quiet, even at high performance levels. This allows you to work next to Biometra TRobot II concentrated!

Analytik Jena
Biometra TRobot II Series

Ensured work success thanks to reproducible, reliable results in high quality

Win walk-away time thanks to the possibility of reliable unattended 24/7 operation

Convenient operation by dedicated software or via complete integration into scheduler software

Minimum downtime thanks to more than 30 years of experience in thermal cycler development and robust equipment design.

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Products

 Biometra TRobot II 384 G, 230 V
Biometra TRobot II 384 G, 230 V
384 well block format for high-throughput applications in research and routine.
It is available as 100 V, 115 and 230 V.
 Biometra TRobot II 96 G, 230 V
Biometra TRobot II 96 G, 230 V
96 well block format for standard applications in research and routine.
It is available as 100 V, 115 and 230 V.
 Biometra TRIO 30, 230 V
Biometra TRobot II 96 SG, 230 V
96 well silver block for highest demands in research and routine.
It is available as 100 V, 115 and 230 V.
 Biometra TRobot II Controller 230 V
Biometra TRobot II Controller 230 V
Controller for Biometra TRobot II block modules.
It is available as 100 V, 115 and 230 V.
 Biometra TRobot II PCR Module 384 G
Biometra TRobot II PCR Module 384 G
Biometra TRobot II PCR module with 384 well block with gradient function.
 Biometra TRobot II PCR Module 96 G
Biometra TRobot II PCR Module 96 G
Biometra TRobot II PCR Module with 96 well aluminum block with gradient function
 Biometra TRobot II PCR Module 96 SG
Biometra TRobot II PCR Module 96 SG
Biometra TRobot II PCR Module with 96 well silver block with gradient function

TECHNICAL SPECIFICATIONS

Integration software

Sample Block

Block capacity

Proposed sample volume

Maximum Heating

Average Heating

Dimension (width x depth x height)

Maximum Cooling

Average Cooling

Temperature uniformity

Gradient

Max./Min. gradient

Adjustable gradient range

Block exchange

Tempering method

Standby temperature

Temperature control mode

Adjustable temperature range

Temperature control accuracy

Lid type

Space requirement (width x depth x height)

Lid temperature

Contact pressure

Compatible sealing systems

Plate lifter

Consumable compatibility

Time increment

Temperature increment/decrement

Additional dimensions

Required clearance zone

Biometra TRobot II 384 G, 230 V

Biometra Library (dll file) for integration into an automation system's scheduler software Aluminum, special alloy 384 well microplate 5 - 25 µL 2.4 °C/s 2.2 °C/s 208 mm x 260 mm x 206 mm 1.8 °C/s 1.6 °C/s +/- 0,15 °C at 55 °C after 15 s yes 18 °C/0,1 °C 24 rows 20 °C to 99 °C no Peltier elements Down to 4 °C Control Mode 3 - 99 °C +/- 0,1 °C Motorized lid with heating module, which is connected spring-loaded to the lid 208 mm x 332 mm x 291 mm 30 - 110 °C Independent from the used consumable adjusted via software in the range of 4 kg to 12 kg. Typical standard settings: 8 kg to 10 kg Sealing foils and mats Motor-driven, direct compatible with full-skirted PCR plates.With optional Biometra TRobot II adapter frame also compatible with semi-skirted PCR plates with these dimensions: distance well tip to semi-skirt: 12 to 14 mm with 96-well aluminum block, 11 to 13 mm with 96 well silver block. 384 well PCR microplates 1 - 240 s/cycle +/- 0,1 °C to 20 °C per cycle Controller (W x D x H, mm): 240 x 387 (444 incl. cable ports) x 139 PCR module: 20 cm at the rear side. When operating several units side by side, an additional 10 cm between the units. Controller: 10 cm at the rear side

Biometra TRobot II 96 G, 230 V

Biometra Library (dll file) for integration into an automation system's scheduler software Aluminum, special alloy 96 x 0,2 mL tubes, 96 well microplates or 8 well strips 5 - 50 µL 4.0 °C/s 3.7 °C/s 208 mm x 260 mm x 206 mm 3.1 °C/s 2.8 °C/s +/- 0,20 °C at 55 °C after 15 s yes 24 °C/0,1 °C 12 rows 10 °C to 99 °C no Peltier elements Down to 4 °C Block Control 3 - 99 °C +/- 0,1 °C Motorized lid with heating module, which is connected spring-loaded to the lid 208 mm x 332 mm x 291 mm 30 - 110 °C Independent from the used consumable adjusted via software in the range of 4 kg to 12 kg. Typical standard settings: 8 kg to 10 kg Sealing foils and mats Motor-driven, direct compatible with full-skirted PCR plates.With optional Biometra TRobot II adapter frame also compatible with semi-skirted PCR plates with these dimensions: distance well tip to semi-skirt: 12 to 14 mm with 96-well aluminum block, 11 to 13 mm with 96 well silver block. Low-profile and high-profile PCR plates with full-skirt, semi-skirt and without skirt 1 - 240 s/cycle +/- 0,1 °C to 20 °C per cycle Controller (W x D x H, mm): 240 x 387 (444 incl. cable ports) x 139 PCR module: 20 cm at the rear side. When operating several units side by side, an additional 10 cm between the units. Controller: 10 cm at the rear side

Biometra TRobot II 96 SG, 230 V

Biometra Library (dll file) for integration into an automation system's scheduler software Silver block with gold coating 96 x 0,2 mL tubes, 96 well microplates or 8 well strips 5 - 100 µL 5.0 °C/s 4.9 °C/s 208 mm x 260 mm x 209 mm 4.8 °C/s 4.5 °C/s +/- 0,15 °C at 55 °C after 15 s yes 30 °C/0,1 °C 12 rows 10 °C to 99 °C no Peltier elements Down to 4 °C Block Control 3 - 99 °C +/- 0,1 °C Motorized lid with heating module, which is connected spring-loaded to the lid 208 mm x 332 mm x 291 mm 30 - 110 °C Independent from the used consumable adjusted via software in the range of 4 kg to 12 kg. Typical standard settings: 8 kg to 10 kg Sealing foils and mats Motor-driven, direct compatible with full-skirted PCR plates.With optional Biometra TRobot II adapter frame also compatible with semi-skirted PCR plates with these dimensions: distance well tip to semi-skirt: 12 to 14 mm with 96-well aluminum block, 11 to 13 mm with 96 well silver block. Low-profile and high-profile PCR plates with full-skirt, semi-skirt and without skirt 1 - 240 s/cycle +/- 0,1 °C to 20 °C per cycle Controller (W x D x H, mm): 240 x 387 (444 incl. cable ports) x 139 PCR module: 20 cm at the rear side. When operating several units side by side, an additional 10 cm between the units. Controller: 10 cm at the rear side

Biometra TRobot II Controller 230 V

240 x 387 (444 incl. cable ports) x 139 (W x D x H, mm) 10 cm at the rear side

Biometra TRobot II PCR Module 384 G

208 x 260 x 209 (mm) 20 cm to the rear. When operating several units side by side, an additional 10 cm between the units.

Biometra TRobot II PCR Module 96 G

208 x 260 x 209 (mm) 20 cm to the rear. When operating several units side by side, an additional 10 cm between the units.

Biometra TRobot II PCR Module 96 SG

208 x 260 x 209 (mm) 20 cm to the rear. When operating several units side by side, an additional 10 cm between the units.
 Biometra TRobot II Series

Technology Highlights

Smart Tune Lid concept

The unique arc-shaped opening movement has many advantages: In addition to a low instrument height, the sample block is completely accessible for the gripper from three sides. The vertical closing of the lid with software adjustable pressure on the sample plate ensures completely uniform conditions in all sample positions regardless of the height of the plate and sealing material. This feature ensures best reproducibility of results. The particularly robust and patent-pending single-motor mechanism is ideally designed for 24/7 use.

Smart release of plates

For a workflow without interruptions it is very important that the sample plate can be removed smoothly from the block. Since plates can get stuck on the block after long incubation at different temperatures, the Biometra TRobot II contains a patent-pending system with four small motor-driven plate lifters. When the lid is opened, they gently lift the plate out of the block and are then immediately recessed. This unique system is compatible with all full-skirted plates. A simple adapter frame is available for half-skirted plates.

Software

Biometra TSuite

User-friendly software for operating thermal cyclers in a network

The Biometra TRobot II is completely controlled by external software – typically integrated into the robot software or via the Biometra TSuite computer software. This software offers a full range of functions for controlling the cycler, creating programs, managing the device and documenting its relevant states and actions in detail. Encrypted data transmission ensures the integrity and security of your data. Various log files enable GMP-compliant use and, in the event of malfunction, help locate the cause of the error prior to a service visit. The number of addressable instruments is almost unlimited – up to 1,000 devices can be managed by the software.

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